... to the interface of the bilayer at the beginning of the simulation) ` and the study by Berneche et al [16] With respect to the behavior of the lipids, we make the same observation that those of ... between the dimensions of the system and the number of water molecules aiming to examine whether or not the asymmetry of the system and increased solvation would affect the dynamics of the lipids ... period The final conformation of the peptide is representative of the last 50 ns of the trajectories because most of the prominent secondary structure changes occurred during the first half of each...
Ngày tải lên: 18/02/2014, 08:20
... secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility given to the ... research, dedicated to the furtherance of science and technology and to their use for the general welfare Upon the authority of the charter granted to it by the Congress in 1863, the Academy has a ... NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences,...
Ngày tải lên: 23/03/2014, 01:20
Báo cáo khoa học: "DEVOTED TO THE TRANSLATION OF LANGUAGES BY THE AID OF MACHINES" potx
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: "DEVOTED TO THE TRANSLATION OF LANGUAGES BY THE AID OF MACHINES" pot
... are plans to form shortly a working committee of HAS, for the purpose of theoretically co-ordinating all of the Hungarian work in MT and mathematical linguistics György Szépe November, 1962 ... addition, there are many persons, some of whom are not associated directly with the above-mentioned groups, who are working on related problems There are plans to form shortly a working committee of ... quantitative linguistics The prospect is 32 that this group will form an official liaison with HAS (4) Technical University of Budapest, Institute of Languages Includes a group, headed by György Hell,...
Ngày tải lên: 23/03/2014, 13:20
The use of technology by the elderly pdf
... phones Similar to the present findings, the results of the by the Statistical Office of Finland showed that 30% of the elderly women used washing machines, whereas 7% of men used these electrical ... Social Sciences SPSS 15 was used for the statistical processing of the data The chi‐squared test was used for testing the hypothesis of The use of technology by the elderly pp:118-126 E-ISSN:1791-809X ... interview of the researcher, after having given the necessary information, clearly explained the objectives of the survey and ensured anonymity of the respondents The completion of the questionnaires...
Ngày tải lên: 28/03/2014, 19:21
Research report: "To study the effect of substituents on the properties of aniline by the method of approximate quantum AM1" pps
... substituents enhance planarity of the aniline framework, thereby shortening d(CN) The accompanying loss of electron density from the amino nitrogen atom decreases the pKa of the amino group Conversely, ... Correlation of the dipole moment with the Hammett constants of the substituents It is evident from the table II that electron-donating substituents on the phenyl ring increase the pKa of anilines ... Fugure Correlation of the bond length d(C-N) with the Hammett constants of the substituents The para substituents show a much better correlation with d(C-N) (R2 = 0.9454) than the meta substituents...
Ngày tải lên: 23/07/2014, 13:21
báo cáo khoa học: " Factors influencing the production of stilbenes by the knotweed, Reynoutria × bohemica" pps
... the pot wall, for chemical analyses The ramification of the branches was also taken into account; the lengths of all the main branches rising from the soil, as well as the lengths of all of the ... accordance with the evidence brought by [27] indicating that N limitation might occur when the N:P ratio is as high as 5.8 On the other hand, the nitrogen and phosphorus contents of all of the other (low-organic) ... studying the potential of “inland” sources of resveratrol in R × bohemica, we also Page of 16 wanted to determine the content of other stilbenes in this plant and to assess the contributions of its...
Ngày tải lên: 12/08/2014, 03:21
Báo cáo y học: " Reduction of exacerbations by the PDE4 inhibitor roflumilast - the importance of defining different subsets of patients with COPD" pps
... responsibility for the integrity of all of the data and the accuracy of the data analysis, including and especially any adverse effects DB contributed to the conception and design of these studies, the acquisition ... final approval of its content ahead of submission U-MG contributed to the conception and design of these studies, the acquisition of study data, and the analysis and interpretation of these data ... conception and design of these studies, the acquisition of study data, and the analysis and interpretation of these data He was fully involved in the drafting and revision of this manuscript, and...
Ngày tải lên: 12/08/2014, 13:22
Báo cáo khoa học: Formation of highly toxic soluble amyloid beta oligomers by the molecular chaperone prefoldin pptx
... expressed in the human brain [42], our results suggest a possible involvement of PFD in the formation of toxic Ab oligomers in the cytosol Results Fibrillation of Ab peptide in the presence of PFD ... Examples of the Ab particles shown in (B) Scale bar = 50 nm ined the cytotoxicity of soluble Ab oligomers produced by the addition of PFD Ab aggregates of various concentrations were added to the ... support the notion that PFD participates in the formation of Ab oligomers within the cytosolic compartment In an effort to elucidate the mechanism pertaining to the PFD-induced formation of high-molecular-mass...
Ngày tải lên: 07/03/2014, 04:20
Báo cáo khoa học: Cupiennin 1a, an antimicrobial peptide from the venom of the neotropical wandering spider Cupiennius salei, also inhibits the formation of nitric oxide by neuronal nitric oxide synthase pptx
... that of Ca2+-CaM [10,11,25,26], and therefore adversely affects binding of CaM to the Ca2+-CaM-binding domain of nNOS CaM is not only essential for the operation of nNOS and the other NOS isoforms, ... of the target peptide This is shown in Fig 4B for the 20residue binding domain of the plasma membrane Ca2+ pump ⁄ Ca2+-CaM complex, where the first 12 residues of the peptide are encompassed by ... this type of structure is also adopted by Ca2+-CaM when it binds to the CaM-binding domain of endothelial nitric oxide synthase (eNOS) [33] The second example is when the C-terminal lobe of Ca2+-CaM...
Ngày tải lên: 23/03/2014, 09:21
Báo cáo Y học: Suppression of apolipoprotein C-II amyloid formation by the extracellular chaperone, clusterin potx
... reduces the overall size of the fibrils formed even though amyloid formation remains highly cooperative While incubation of apoC-II in the presence of clusterin reduces the size distribution of the ... for the effects of a-crystallin upon amyloid formation by apoC-II [18] Although the serum and seminal forms of clusterin are encoded by the same structural gene, they are known to differ in their ... (Fig 1B) The specificity of the inhibition of amyloid formation by clusterin was assessed in control experiments using BSA The presence of BSA (100 lgÆmL)1) had negligible effect on the time-dependent...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo khoa học: Aspergillus nidulans a-galactosidase of glycoside hydrolase family 36 catalyses the formation of a-galacto-oligosaccharides by transglycosylation doc
... lacking the 6-hydroxymethyl group Noticeably, the axial 1-OH of a-galactose projects out of the active site in the model and the catalytic nucleophile Asp511 together with Trp221, from the N-terminal ... intermediate by direct attack at the anomeric centre In the next step, water is deprotonated by the general base catalyst and attacks the anomeric centre, releasing the carbohydrate moiety For GH36, the ... complexes of GH27 were performed to illustrate the donor and acceptor specicity and the regioselectivity of AglC Results and Discussion Sequence similarity of AglC The amino acid sequence of AglC,...
Ngày tải lên: 29/03/2014, 21:20
Báo cáo khoa học: In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS–HSP90 heterocomplex pot
... aorta The level of HSP90 and the type of NOS isoform present in rat brain and aorta were determined by immunoblotting (Fig 1) In brain, nNOS was the most preferentially expressed isoform, together ... in these digestion processes was demonstrated by the protective effect on both HSP90 and NOS degradation of the administration to the HSD-treated NMS animals of C.I.1 (Fig 5) In the brain of ... to explore the relationship between the HSP90 to NOS ratio and the formation of calpainresistant heterocomplexes, we first studied, by immunoprecipitation analysis, the association of the two proteins...
Ngày tải lên: 30/03/2014, 04:20
báo cáo hóa học:" Transcriptional regulation of bone formation by the osteoblast-specific transcription factor Osx Chi Zhang" pptx
... expression of type I collagen (Col1a1) in the condensed mesenchyme of the membranous skeleton and the periosteum and mesenchyme of the endochondral skeleton is severely reduced Expressions of the osteoblast-specific ... regulator of postnatal bone mass 11 Dlx5 delayed ossification of the roof of the skull and abnormal osteogenesis positive regulator in OB differentiation 12 reading frame (ORF) and 3-prime UTR The ... Osx-null embryos the number of TRAP-positive cells appear to be reduced compared to wild-type embryos In long bones of Osxnull embryos cells from the periosteum invade the zone of the hypertrophy...
Ngày tải lên: 20/06/2014, 04:20
Báo cáo hóa học: " Effects of rehydration nutrients on H2S metabolism and formation of volatile sulfur compounds by the wine yeast VL3" docx
... previous hypothesis of distinct effects for each of the treatments and further suggest the presence of an additional nutrient factor regulating the formation of H2S Confirmation of the microarray ... observations at the sampling point where the addition of rehydration nutrients induced the formation of H2S while the addition of DAP delayed it Page of 11 (Figure 1c) Nonetheless, these results ... concentration of higher alcohols was decreased (Additional file 1) Further characterisation of the effect of rehydration nutrients on the formation of volatile sulfur compounds was obtained by monitoring...
Ngày tải lên: 20/06/2014, 23:20
Báo cáo y học: "Surgical outcomes of the brachial plexus lesions caused by gunshot wounds in adults" pdf
... reconstruction of the nerve was also the best treatment of the pain In our patients, the early exploration and reconstruction of the brachial plexus not only improved the function of the arm but ... length of the nerve graft to get good clinical outcome (Table 7) However, the p value was 0.055 for the comparison of the relationship between the length of the graft and the final outcome, and the ... inspection of the overall symmetry and observation of obvious scars related to either the initial trauma or subsequent surgery The range of motion of all joints and the neck were assessed The supraclavicular...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: "Compression of the lower trunk of the brachial plexus by a cervical rib in two adolescent girls: case reports and surgical treatment." pot
... on the left side of the 17 year old supraclavicular Exploration of the brachial plexus through a girl Exploration of the brachial plexus through a supraclavicular approach on the left side of the ... to the ventral edge of the cervical rib and the bony process from the first rib (Fig 5) The main part of the cervical rib including the bone process from the first rib was resected after the ... around the pseudoarthrotic bone formation There were no similar findings of the brachial plexus on the left side despite the presence of a cervical rib When the patient was 12 years old, the cervical...
Ngày tải lên: 10/08/2014, 10:20
báo cáo khoa học: " Insight into the early steps of root hair formation revealed by the procuste1 cellulose synthase mutant of Arabidopsis thaliana" doc
... [4,5] The formation of double hairs by a proportion of prc1-1 epidermal cells (Fig 2E) indicates that the control of the site of hair initiation is affected To test this, the position of hair formation ... root hair formation in wild-type and can result in the restoration of hair formation in rhd6 [6] This raised the question of whether the partial restoration of hair formation in rhd61 by prc1-1 ... to the expression pattern or activity of one of the other CesA proteins or other important factors cannot be ruled out However, alteration of the cellulose composition of the cell wall is not the...
Ngày tải lên: 12/08/2014, 05:20