... testing and adjuvant chemotherapy for breast cancer patients in New Hampshire Methods: We examined New Hampshire State Cancer Registry data on 5630 female breast cancer patients diagnosed from ... Receiving chemotherapy Receipt of chemotherapy was documented in 2264 (40.2%) patients in the breast cancer cohort, and 336 (22.2%) of patients who received ODX Receipt of chemotherapy among patients ... the adjusted model (Table S2) Chemotherapy recommendation Chemotherapy was recommended for 2701 (48.0%) patients in the breast cancer cohort and 459 (30.4%) of patients who received ODX In the
Ngày tải lên: 28/09/2020, 09:41
... and mortality rate of breast cancer are still raising [1] In 2013, breast cancer accounted for 25 % of total cancer cases and 15 % of cancer-related deaths worldwide [1] For decades, surgical ... Min et al BMC Cancer (2016) 16:717 Background Breast cancer is the most frequently diagnosed cancer among females worldwide [1] In more developed countries like the U.S., breast cancer death rates ... and improve the prognosis of patients with breast cancer, it is also notorious for comprehensive side effects, hence only a selected group of patients can benefit Therefore, the screening of molecular
Ngày tải lên: 20/09/2020, 17:57
Multivariable regression analysis of febrile neutropenia occurrence in early breast cancer patients receiving chemotherapy assessing patient-related, chemotherapy-related and
... develop risk models for the occurrence of FN in breast cancer patients receiving Page of 11 FEC chemotherapy in any cycle and the first cycle based on a large set of patient-related, chemotherapy-related, ... Stage I-IIIC) breast cancer patients treated between 2000 and 2010 at the Leuven Multidisciplinary Breast Cancer Center of the University Hospitals Leuven, Belgium Consecutive patients were included ... identify patients at high risk of FN before the initiation of chemotherapy to provide them with appropriate prophylactic measures Risk models for the occurrence of CIN [9] and FN [10] in patients
Ngày tải lên: 05/11/2020, 00:50
Circulating tumor microemboli (CTM) and vimentin+ circulating tumor cells (CTCs) detected by a size based platform predict worse prognosis in advanced colorectal cancer patients during chemotherapy
... colorectal cancer (CRC) patients during chemotherapy Methods: A size-based platform for CTC isolation was applied PB samples (5 ml) from 98 advanced CRC patients during 2–6 cycles chemotherapy ... circulating tumor cells (CTCs) detected by a size‑based platform predict worse prognosis in advanced colorectal cancer patients during chemotherapy Dejun Zhang1†, Lei Zhao1†, Pengfei Zhou2, Hong Ma1, ... significance on survival in 32 CTCs-positive patients with advanced CRC Results: Forty-eight of 98 patients were CTCs-positive, including 18 CTM-positive patients, and CTC detection was positively
Ngày tải lên: 19/11/2022, 11:47
Age-related microRNAs in older breast cancer patients: Biomarker potential and evolution during adjuvant chemotherapy
... adjuvant chemotherapy (docetaxel and cyclophosphamide, TC) for invasive breast cancer (chemo group, CTG, n = 46) A control group of older breast cancer patients without chemotherapy was included for ... and cancer, but the impact of chemotherapy on age-related miRNAs has barely been studied Our aim was to examine whether chemotherapy accelerates the aging process in elderly breast cancer patients ... originally of 57 patients, and miRNA data were available at the time points in 46 patients In parallel, a comparable series of patients, not eligible for systemic chemotherapy, but only for endocrine
Ngày tải lên: 03/07/2020, 00:52
Weight change during chemotherapy in breast cancer patients: A meta-analysis
... gain in women with breast cancer during chemotherapy [1–8] Several reviews reported body weight gain during chemotherapy for breast cancer patients [9–15] Weight gain during chemotherapy was first ... weight gain during chemotherapy for women with early stage breast cancer Treatment for breast cancer has changed over time Before the 1990s, only CMF was used as chemotherapy regime, while during ... before, during and after chemotherapy Page of 13 Reviews regarding body weight gain during chemotherapy for breast cancer patients were narrative reviews and did not provide summary estimates for
Ngày tải lên: 19/09/2020, 21:45
Prognostic impact of AJCC response criteria for neoadjuvant chemotherapy in stage II/III breast cancer patients: Breast cancer subtype analyses
... BMC Cancer (2016) 16:515 DOI 10.1186/s12885-016-2500-1 RESEARCH ARTICLE Open Access Prognostic impact of AJCC response criteria for neoadjuvant chemotherapy in stage II/III breast cancer patients: ... of neoadjuvant chemotherapy before definitive surgery, the patients were reexamined for response evaluation Thereafter, the patients received curative surgery followed by adjuvant chemotherapy ... prognostic information In this study, we classified breast cancer patients into four subgroups, namely luminal A (LA), luminal B (LB), HER2 enriched (HER2), and triple-negative breast cancer (TNBC),
Ngày tải lên: 20/09/2020, 14:08
Implication from thyroid function decreasing during chemotherapy in breast cancer patients: Chemosensitization role of triiodothyronine
... in breast cancer patients at initial diagnosis and during chemotherapy Page of 12 According to the changes of thyroid hormones during chemotherapy, the effect of T3 on sensitity of breast cancer ... serum samples of breast cancer patients and 316 samples of breast benign lesion patients at initial diagnosis were analyzed for thyroid hormones Thirty-seven of 224 breast cancer patients were diagnosed ... which may provide a new adjuvant therapy for breast cancer in furture, especially for those have hypothyroidism during chemotherapy Keywords: Breast cancer, Thyroid hormones, Non-thyroidal illness
Ngày tải lên: 05/11/2020, 06:53
Báo cáo y học: "Down-regulation of kallikrein-related peptidase 5 (KLK5) expression in breast cancer patients: a biomarker for the differential diagnosis of breast lesions" doc
... histological features of breast cancer patients, aiming to examine its clinical value for the discrimination of the cancerous from non-cancerous breast lesions Materials and methods Breast tissue specimens ... expression prognostic value in breast cancer patients, whereas the KLK5 expression quantification proved to be an independent biomarker for the prediction of breast cancer patients’ DFS and OS [30] ... physiology and cancer Therefore, KLK5 expression quantification is critical for both the discovery of the early cellular and molecular alterations in breast cancer cells, as well as for the identification
Ngày tải lên: 13/08/2014, 13:20
Exploring Factors Influencing Resilience in Women who Completed Chemotherapy for Breast Cancer in Accra Metropolis
... with Breast Cancer who had Received Chemotherapy 120 5.3 The Support Systems that Influenced Resilience among Breast Cancer Survivors 125 5.4 Adaptation to Breast Cancer Diagnosis and Chemotherapy ... German breast cancer patients Journal of Behavioral Medicine, 29(6), 533-547 200 University of Ghana http://ugspace.ug.edu.gh Appendix A: Background Information form Section A Demographic Information ... http://ugspace.ug.edu.gh Appendix C: Information Sheet and Consent form CONSENT FORM Title: Exploring Factors that Influence Resilience among Breast Cancer Women who Received Chemotherapy in the Accra Metropolis
Ngày tải lên: 31/07/2019, 00:38
Impact of vitamin D on pathological complete response and survival following neoadjuvant chemotherapy for breast cancer: A retrospective study
... breast cancer patients undergoing NAC Keywords: Vitamin D, Neo-adjuvant breast cancer, pCR Background Neoadjuvant chemotherapy (NAC) has become a standard of care in locally advanced breast cancer, ... sufficiency for improving survival of patients with breast cancer Anticancer Res 2014;34:1163–6 30 Vrieling A, Hein R, Abbas S, et al Serum 25-hydroxyvitamin D and postmenopausal breast cancer survival: ... administrated before or during chemotherapy [12] Nevertheless, it has been proven that VD deficiency is extremely frequent in the global population, and even more prevalent in breast cancer patients
Ngày tải lên: 03/07/2020, 01:26
Prediction of survival after neoadjuvant chemotherapy for breast cancer by evaluation of tumor-infiltrating lymphocytes and residual cancer burden
... Asano et al BMC Cancer (2017) 17:888 Page of 10 Fig On ROC curve analyses in all breast cancer and TNBC patients ROC analysis showed that, for all breast cancer patients, the results for the RCB-TILs ... 25] Fortyfive patients had HER2-positive breast cancer and were given additional weekly (2 mg/kg) or tri-weekly (6 mg/kg) trastuzumab during paclitaxel treatment [26] All patients underwent chemotherapy ... RCB-TILs-positive patients than for RCB-TILs-negative patients in all patients (p < 0.001, log-rank) (a), TNBC patients (p < 0.001, log-rank) (b), HER2BC patients (p = 0.007, log-rank) (c), and HRBC patients
Ngày tải lên: 23/07/2020, 23:58
Monitoring the responsiveness of T and antigen presenting cell compartments in breast cancer patients is useful to predict clinical tumor response to neoadjuvant chemotherapy
... signed an informed consent form before blood samples were taken A total of 560 patients with pathological diagnosis of breast cancer were interviewed at the Instituto Nacional de Cancerología ... survey the recovery of immune surveillance and to predict tumor response during A/C chemotherapy Keywords: Breast cancer, Chemotherapy, Neoadjuvant, T cells, Dendritic cells, Doxorubicin, Immune-monitoring ... immunological performance of T and APC compartments in peripheral blood of these patients before and after chemotherapy We found that the overall suppression of these two compartments perceived before treatment
Ngày tải lên: 24/07/2020, 00:17
Efficacy of a hypnosis-based intervention to improve well-being during cancer: A comparison between prostate and breast cancer patients
... studies focus on breast cancer patients However, it is important to test if an effective intervention for breast cancer patients could also have benefits for prostate cancer patients Methods: ... for the breast cancer patients, they took place every weeks It means that for prostate cancer patients, the intervention lasted months (1 session per month), and that for breast cancer patients ... interventions for cancer patients according to their gender As our results suggest, an intervention efficient for breast cancer patients could not be pertinent for prostate cancer patients Several
Ngày tải lên: 24/07/2020, 01:47
Temporal influence of endocrine therapy with tamoxifen and chemotherapy on nutritional risk and obesity in breast cancer patients
... and obesity and its association with CT in breast cancer patients Methods: In this cross-sectional study, 84 breast cancer surviving women were evaluated during endocrine therapy with TMX Anthropometric, ... stated Lima et al BMC Cancer (2017) 17:578 Background Breast cancer (BC) accounts for 29% of all new cases of cancer in women, being the second leading cause of death [1] In patients treated with ... Quantification of nutrients was performed through Dietpro® software, version 5.7, using as a reference, preferably, the Brazilian Table of Food Composition [35] However, for those foods not found in this
Ngày tải lên: 06/08/2020, 05:02
Exercise as a diagnostic and therapeutic tool for preventing cardiovascular morbidity in breast cancer patients – the BReast cancer EXercise InTervention (BREXIT) trial protocol
... endocrine therapy for breast cancer J Natl Cancer Inst 2008;100(4):252–60 Colzani E, Liljegren A, Johansson ALV, Adolfsson J, Hellborg H, Hall PFL, Czene K Prognosis of patients with breast cancer: causes ... questionnaires have been validated for use in cancer patients [67–69] Diet, physical activity and sedentary behaviour 24-h food recall Diet will be assessed by a 24-h food recall completed using the ... KD, Jemal A Cancer statistics, 2016 CA Cancer J Clin 2016; 66(1):7–30 Australian Institute of Health and Welfare Cancer Australia: Breast cancer in Australia Cancer series no 71 Edited by AIHW,
Ngày tải lên: 06/08/2020, 05:32
Current guidelines for BRCA testing of breast cancer patients are insufficient to detect all mutation carriers
... [26] Methods Patients During the study period, a total of 1371 BC patients were tested Two cohorts of patients are described in this report: Cohort 1: Patients tested at The Breast Cancer Surgery ... ovarian cancer [13–22] The American Society of Clinical Oncology (ASCO), The National Comprehensive Cancer Network (NCCN) in the US and the Norwegian Breast Cancer Group (NBCG) all have guidelines for ... Grindedal et al BMC Cancer (2017) 17:438 DOI 10.1186/s12885-017-3422-2 RESEARCH ARTICLE Open Access Current guidelines for BRCA testing of breast cancer patients are insufficient to
Ngày tải lên: 06/08/2020, 06:03
Influence of chemotherapeutic drug-related gene polymorphisms on toxicity and survival of early breast cancer patients receiving adjuvant chemotherapy
... patients Keywords: Early breast cancer, Polymorphisms, Adjuvant chemotherapy, Toxicity, Prognosis Background Breast cancer (BC) currently accounts for 20% of all female cancers worldwide and is ... was performed for MTHFR, RFC1 and GSTP1, while PCR for TS, GSTT1 and GSTM1 genes Results: Among the 244 patients consecutively enrolled, 48.7% were treated with FEC and 51.3% with CMF Patients ... associated with toxicity and survival in patients with early breast cancer (EBC) treated with adjuvant chemotherapy (CT) Methods: This prospective trial included patients with stage I–III BC subjected
Ngày tải lên: 06/08/2020, 06:25
Pretreatment glycemic control status is an independent prognostic factor for cervical cancer patients receiving neoadjuvant chemotherapy for locally advanced disease
... survival outcomes for LACC patients [20] There are reports that cancer patients with hyperglycemia have a poor response to chemotherapy [6, 21–23] Moreover, for diabetic cancer patients, poor glycemic ... of survival and tumor response to chemotherapy for patients receiving NACT for LACC Keywords: Diabetes mellitus, Hemoglobin A1c, Cervical cancer, Neoadjuvant chemotherapy, Prognosis * Correspondence: ... response to chemotherapy in patients receiving neoadjuvant chemotherapy (NACT) for locally advanced cervical cancer (LACC) Methods: A retrospective cohort study was conducted to examine LACC patients
Ngày tải lên: 06/08/2020, 06:36
The E2F4 prognostic signature predicts pathological response to neoadjuvant chemotherapy in breast cancer patients
... and RD patients, we calculated an E2F4 iRAS for each tumor in the Hatzis et al dataset, which contains gene expression and clinical information for patients who underwent neoadjuvant chemotherapy ... chemotherapy response in breast cancer E2F4 individual regulatory activity scores were calculated for 1129 patient samples across independent breast cancer neoadjuvant chemotherapy datasets Accuracy ... managing patients with earlystage breast cancer [1] In large or inoperable tumors, this therapy has been shown to substantially reduce tumor size allowing for easier removal and potentially breast
Ngày tải lên: 06/08/2020, 07:53