... Ca2+ influx via SOC appears to be a determinant in maintaining a sustained increase in [Ca2+]i and regulation of vascular tone and arterial wall structure [17] Elevated influx of Ca2+ via SOC in ... neomuscularization in hypoxia and monocrotaline models of pulmonary hypertension [2,33] Several studies concerning the remodeling process revealed more promising options for therapy in addition to the ... prostacyclin, nitric oxide (NO)/cyclic guanosine monophosphate (cGMP) and endothelin pathways have been shown of pathological importance and involved in the abnormal proliferation and contraction of...
Ngày tải lên: 12/08/2014, 14:20
... Rowe, J Gonzalez, and F Xavier Roca, “3D action modeling and reconstruction for 2D human body tracking,” in Proceedings of the 3rd International Conference on Advances in Patten Recognition (ICAPR ... Nakaoka, and K Ikeuchi, “Matching and blending human motions using temporal scaleable dynamic programming,” in Proceedings of the IEEE/RSJ International Conference on Intelligent Robots and Systems ... the main modes of variation for the walking action obtained from PCA explain the combined motion of both the legs and the arms, while in the bending action they mainly correspond to the motion of...
Ngày tải lên: 21/06/2014, 19:20
Báo cáo khoa học: " Expression of pituitary adenylate cyclase activating polypeptide and its type I receptor mRNAs in human placenta" doc
... washed with 0.1 M PBS, and treated proteinase K, TE buffer, and an acetylation solution Sections were covered with prehybridization buffer containing 50% deionized formamide and incubated at 37oC ... villi and terminal villi during pregnancy In conclusion, our findings suggest that PACAP may have an important role in physiological function of the placenta for gestational maintenance and fetal ... peptide), showing increasedadenosine 3',5'-monophosphate and interleukin-6 secretion and cell proliferation Endocrinology 1993, 133, 2150-2155 18 Miyata A, Arimura A, Dahl RR, Minamino N, Uehara...
Ngày tải lên: 07/08/2014, 18:21
báo cáo khoa học: "First-in-class, first-in-human phase I results of targeted agents: Highlights of the 2008 American Society of Clinical Oncology meeting" pot
... than months (one mesothelioma patient and one colon cancer patient) PF-00562271, a focal adhesion kinase inhibitor Focal adhesion kinase (FAK) is a non-receptor protein tyrosine kinase located in ... Limited, Twinstrand Therapeutics Authors' contributions AM collected and assembled the data, and participated in conception and design, data analysis and interpretation, and manuscript writing LS ... again representing potential for predicting clinical response and for proving mechanisms of action Serum levels of activated CD8 cells and VEGF- A increased after administration of BMS-663513 and...
Ngày tải lên: 10/08/2014, 22:20
Báo cáo y học: "CD4+ T cells spontaneously producing human immunodeficiency virus type I in breast milk from women with or without antiretroviral drugs" potx
... single dose of nevirapine during labor/delivery The remaining women were eligible for ART during pregnancy and received zidovudine, lamivudine and ritonavir-boosted lopinavir The mean duration ... supernatants and two breast milk-derived supernatants, demonstrating the infectiousness of the virus Successful in vitro infections were obtained using samples from women not receiving ART The resulting ... during lactation is ineffective at suppressing cell-associated virus replication and thus may incompletely inhibit the breastfeeding transmission of HIV-1 The evaluation of alternative prevention...
Ngày tải lên: 13/08/2014, 01:20
Báo cáo y học: " Caspase-3-mediated cleavage of p65/RelA results in a carboxy-terminal fragment that inhibits IκBα and enhances HIV-1 replication in human T lymphocytes" ppsx
... activation of HIV-1 in T cells [11] In fact, although the HIV-1 LTR contains several additional DNA binding domains that bind other cellular transcriptional factors, only NF-κB and Sp1 binding sites ... 1,0 Figure Binding affinity assay of p65wt-tag and ΔNH2p65-tag to IκBα by using in vitro translated proteins Binding affinity assay of p65wt-tag and ΔNH2p65-tag to IκBα by using in vitro translated ... coding region was confirmed by DNA-sequence analysis in all substitution mutants The p50wt gene was obtained from pRSV-NF-κB(p105) and cloned in pcDNA3.1 using HindIII/XbaI cloning sites In vitro...
Ngày tải lên: 13/08/2014, 05:21
Báo cáo y học: "Microarray study reveals that HIV-1 induces rapid type-I interferon-dependent p53 mRNA up-regulation in human primary CD4+ T cells" doc
... likely occurring in uninfected/ bystander cells given that a 1.5-fold increase in the number of infected cells is seen at 24 h post-infection with ICAM-1-bearing virions compared to infection with ... showed induction of type-I IFN by HIV-1 in our cell culture system and a complete inhibition of the HIV-1-mediated increase in p53 gene expression in presence of a combination of blocking antibodies ... HIV-1-mediated induction of p53 expression at the mRNA and protein levels Indeed, a to 5-fold increase in p53 mRNA was detected as early as h following HIV-1 infection while an induction of p53 at...
Ngày tải lên: 13/08/2014, 05:21
Báo cáo y học: " Open Access Quantification of the virus-host interaction in human T lymphotropic virus I infection" pdf
... expression exposes infected cells to the CTL response it also increases infected cell proliferation by upregulating cellular genes involved in proliferation and deregulating cell cycle checkpoints ... mRNA Measuring Tax protein expression by flow cytometry also provides information at a per cell level enabling us to determine whether an increase in Tax expression is due to an increase in the number ... expression = high) Authors' contributions Using this model the fraction of the observed variation in proviral load that could be explained by the variation in CTL lysis rate and rate of Tax expression...
Ngày tải lên: 13/08/2014, 09:21
Báo cáo y học: " Role of Tax protein in human T-cell leukemia virus type-I leukemogenicity" pps
... phase includes phosphorylation of IκBα on serine32 and serine36 and of IκB β on serine19 and serine23 (Fig 3, No 6), which is followed by their ubiquitination and subsequent proteosomal degradation ... reticulum (ER) and is associated with two ER-resident proteins; calerticulin and calnexin Calerticulin is a calcium-binding protein that participates in calcium signaling and linked to activation of the ... [28] by binding to a Rex responsive element (RxRE) residing in the 3' R region of the viral RNA [29] In addition, there are some indications that Rex may also inhibit splicing and degradation of...
Ngày tải lên: 13/08/2014, 13:20
Cambridge.University.Press.Who.Believes.in.Human.Rights.Reflections.on.the.European.Convention.Oct.2006.pdf
... xx xxvii Introduction The Convention in outline 19 The Convention in a realist light 30 The Convention in a utilitarian light 68 The Convention in a Marxist light 114 The Convention in a particularist ... an End Turpin: British Government and the Constitution: Text, Cases and Materials Twining: Globalisation and Legal Theory Twining: Rethinking Evidence Twining & Miers: How to Do Things with Rules ... is a doctrine too Oscillating between universalism and particularism Conclusion 156 157 188 The Convention in a feminist light Feminism and feminisms The feminist liberal agenda: Working for sex...
Ngày tải lên: 21/09/2012, 11:02
Kogan.Page.Managing.Projects.in.Human.Resources.Training.and.Developement.Apr.2006.eBook-DDU.pdf
... Resourcing Managing project activities during implementation Keeping an overview 107 107 108 110 111 112 112 114 10 Monitoring and control Monitoring Milestones Maintaining balance Controlling change ... using computers the training could take too long to meet the needs of their organizations In addition, there was growing demand for training in digital media as the structure of the printing industry ... their time PROJECTS IN HR, TRAINING AND DEVELOPMENT Inevitably, any project that takes place in a setting concerned with training and developing people or managing the performance and welfare of people...
Ngày tải lên: 21/09/2012, 17:33
Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"
... Function Gene ID NM_015456 NM_000213 NM_014393 ▲ 1.52 regulation of transcription protein binding double-stranded RNA binding DNA binding ▼ 5.02 protein binding NM_001149 NM_004242 ▲- increased ... application or the ingestion of ethanol induces a completely different pattern due to the reported ethanol-induced expression and activation of cytokines and chemokines in monocytes and macrophages (including ... limitation of percutaneous ethanol injection, which is only indicated for small and single tumors [45, 46] In conclusion, the functional genomics analysis presented in this investigation confirms...
Ngày tải lên: 31/10/2012, 15:28
SCARAB BEETLES IN HUMAN CULTURE
... grubs found in cattle droppings were also gathered and eaten during the rainy season including the larvae of Oryctes rhinoceros and Xylotrupes gideon (Dynastinae) In Vietnam, according to Bodenheimer ... important sources of mineral salts and vitamins Numerous insects are consumed in Mexico (personal observation; Conconi et al 1984) Indians eat the larvae of Strategus sp in Nayarit and Chiapas, the ... veneration Amulets were worn as protection against evil spells, and several papyrus documents provide information about using scarabs in popular medicine Even today, a cottage industry in Cairo and...
Ngày tải lên: 24/04/2013, 10:07
3D Videocommunication Algorithms concepts and real time systems in human centred communication
... paintings had been a well-known phenomenon since Roman times, and such paintings would create the illusion of, for instance, walls containing a window to the outside world or a ceiling containing ... with intuitive interaction and communication capabilities In the entertainment sector we are now beginning to see the viable economics of highdefinition broadcasting of live events in sports or ... 3.4.1 Head Tracking 3.4.2 View-dependent Rendering 3.4.3 Mask Generation 3.4.4 Texturing 3.4.5 Collision Detection 3.5 Conclusions References 3D in Content Creation and Post-production Oliver Grau...
Ngày tải lên: 12/05/2013, 10:21
ĐỀ ÔN THI HỌC KỲ I in ch hsNăm học 2009
... ( x) = trờn on 0; 16 sin x 4sin x 3 ễN THI HC K I Nm hc 2009-2010 A Phn chung cho cỏc thớ sinh: Cõu I: Cho hm s y = f ( x ) = x x + cú th l ng cong (C) 1) Kho sỏt s bin thiờn v v th ... ) = sin x x trờn on ; 2 10 ễN THI HC K I Nm hc 2009-2010 I PHN CHUNG CHO TT C HC SINH (7,0 im) Cõu I (3.0 im) Cho hm s y = x x cú th (C) Kho sỏt s bin v v th (C) Da vo th (C) bin lun ... trờn on [e , e] -Ht - ễN THI HC K I Nm hc 2009-2010 I PHN CHUNG CHO TT CC HC SINH (7,0 im) Cõu I (3.0 im) Cho hm s y = x + x Kho sỏt s bin thiờn v v th (C) ca hm s Bin lun...
Ngày tải lên: 28/09/2013, 22:10
TRAFFICKING IN HUMAN BEINGS
... Europe (the Helsinki Commission) was established by U.S Congress in 1976 to monitor and report on the implementation of the decisions of the Conference on Security and Cooperation in Europe (C.S.C.E) ... more accessible and inexpensive through telecommunications advances, but the expansion of existing criminal networks is (10)…………… by rapid and enhanced contact-gathering and information exchange ... harbouring of a person involving the (2) of deception, coercion (including the use or threat of force of the abuse of authority) or debt bondage for the (3)………….of placing or holding such person,...
Ngày tải lên: 25/10/2013, 15:20
Introduction of Who Believes in Human Rights
... an enormous success story We are the only institution of this kind and we are an inspiration in other continents’: Fred J Bruinsma and Stephan Parmentier, ‘Interview with Mr Luzius Wildhaber, ... developed and successful international human rights instrument’: ‘The Impact of the European Convention on Human Rights on the International Criminal Tribunal for the former Yugoslavia’, in Paul Mahoney ... first, there is a sense in which one can read whatever one wishes into the Convention (even if the post-modern ring of this observation may not convince everyone); second my analysis, however...
Ngày tải lên: 01/11/2013, 10:20
Projects in human resources training and developement
... Resourcing Managing project activities during implementation Keeping an overview 107 107 108 110 111 112 112 114 10 Monitoring and control Monitoring Milestones Maintaining balance Controlling change ... using computers the training could take too long to meet the needs of their organizations In addition, there was growing demand for training in digital media as the structure of the printing industry ... their time PROJECTS IN HR, TRAINING AND DEVELOPMENT Inevitably, any project that takes place in a setting concerned with training and developing people or managing the performance and welfare of people...
Ngày tải lên: 13/12/2013, 14:58