Báo cáo y học: "Translational Medicine and Reliability of Single-Nucleotide Polymorphism Studies: Can We Believe in SNP Reports or Not"

... of genes to their current genome content (orange parts in graphs of Figure 3). As can be observed, and stated above already, a majority of duplicates in zebrafish are of more recent origin (indicated ... categories with a significantly different number of retained duplicates could be identified. Interestingly, all of the significant differences were observed between fishes on the one hand and...

Ngày tải lên: 14/08/2014, 16:21

... lay still (e.g looking at books or listening to stories) Level Stationary - limb or trunk moving Was stationary but swinging or swaying trunk (e.g standing and singing a song) Was stationary ... activity during the week Parents reported type of activity, duration spent in the activity and the number of times usually spent in the activity each week Other information included how Page of 13 ......

Ngày tải lên: 14/08/2014, 08:20

... pathophysiology in acute asthma in several ways, mainly by modifying the action of inflammatory cells, downreg- ulating the release of proinflammatory cytokines and thereby controlling the airway inflammation ... cyanosis may be present. P6. Alarming obstruction., often both inspiratory and expiratory. Faint respiratory sounds. Chest recessions. Use of auxillary respiratory muscles and high r...

Ngày tải lên: 13/08/2014, 23:20

... mmHg, and an inspiratory oxygen concentration of 30% with a positive end-expiratory pressure of 2 cmH 2 O and an inspira- tory/expiratory ratio of 1:2 were used. Cardiac and respiratory parameters ... we did not investigate the correlation between the number and capacity of EPCs and the other factors of MODS in the present study. The mechanisms for the decrease in the number and function of ....

Ngày tải lên: 13/08/2014, 18:22

... 1 week); a first-degree family his- tory of a psychotic or bipolar disorder; or a personal history of schizotypal personality disorder, with signifi- cant recent functional decline [21]. Analysis ... usually in the category of. .. Continuities and discontinuities in psychopathology between childhood and adult life J Child Psychol Psychiatry 2006, 47(3–4):276-295 Curman H, Nylander ... and 197...

Ngày tải lên: 13/08/2014, 18:21

... association of school refusal with internalizing disorders including anxiety disorders and depression [6-9] and an even stronger association between truancy and externaliz- ing disorders including antisocial ... analyze potential risk, compensatory, vulnerability, and protective factors of psychopathology [5], life events were hypothet- ically seen as stressors, and various psychosocial varia...

Ngày tải lên: 13/08/2014, 18:21

... Pathology, Faculty of Veterinary Medicine, Utrecht University, The Netherlands and 3 Department of Infectious Diseases and Immunology, Division of Virology, Faculty of Veterinary Medicine, Utrecht ... granular cytoplasmic staining in a minority of the cells. As controls for the two stainings, liver tissue and kidney tissue of a healthy dog was used. These were posi- tively and negatively stai...

Ngày tải lên: 13/08/2014, 13:20

... effects were obtained in studies involving patients under- going major abdominal surgery or suffering from acute pancreatitis [39,40]. In contrast, Anderson and coworkers [28] did not observe any measurable ... Marcy l'Etoile, France). Findings of analyses of specimens taken for microbiological diagnosis because of patient infectious status (routinely performed by the hospital laboratory...

Ngày tải lên: 13/08/2014, 11:22

... polyps to cancers, taking into account intervening mortality Thus a proportion of polyps at each stage were assumed to be potentially carcinogenic and placed in a waiting state from which they were ... [22,47-50] (assumed normally distributed with a standard deviation of four years) The incidence of polyps was matched with future incidence of cancers originating from polyps in order to calcul...

Ngày tải lên: 13/08/2014, 11:22

... and JMM have helped in drafting and finalizing the manuscript and provided important input on the design of the study BB conceived the study, participated in its coordination, and ... 91(20):9564-9568 Cantin R, Fortin JF, Tremblay M: The amount of host HLA-DR proteins acquired by HIV-1 is virus strain- and cell type-specific Virology 1996, 218:372-381 Fortin JF, Cantin R, Lamontagne ... stran...

Ngày tải lên: 13/08/2014, 05:22

... to coreceptor binding inhibitors, implying that the receptor/coreceptor binding function was not compromised by linking gp120 and gp41 subunits [115]. These findings suggest that, follow- ing ... structure and conformational flexibility of gp120 resulting in formation of the corecep- tor binding site that permits assembly of ternary gp120- CD4-coreceptor complexes [91-97]. Interestingly, Env...

Ngày tải lên: 13/08/2014, 05:21

... inhibi- tors,proteaseinhibitors(PIs),entryinhibitors,fusion inhibitors and integrase (IN) inhibitors (INIs). Despite this apparent diversit y, the alternatives for HIV-2- infected patients are more ... Double-stranded ODNs were obtained by mixing equimolar amounts of comple- mentarystrandsinthepresenceof100mMNaCl.We carried out 3’-processing and strand transfer assays at 37°C in a buffer cont...

Ngày tải lên: 13/08/2014, 01:21

... intercross of the lines Correlation analysis between expression, proviral integrations and body weight showed that high ALVE levels in the LWS line were inherited and that more ALVE integrations were ... the lines Therefore, we analysed the extent of proviral integration by using qPCR and by analyzing the ALVE env gene content in genomic DNA In addition to the parental lines (G41 and G45), we...

Ngày tải lên: 12/08/2014, 23:21

... Respiratory Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan, 4 Department of Respiratory Medicine, West China Hospital, West China Medical School Sichuan University, Chengdu, ... the inhibitors of apoptosis, while it resulted in no cleavage of PARP or caspase 3. TGF- β1, in contrast, resembled staurosporin by increasing the expression of Bax and initiating the cleavag...

Ngày tải lên: 12/08/2014, 18:20

... factor prominently expressed by the lung that con- tains a winged helix DNA binding domain [4]. Necessary for the formation of foregut derivatives, FoxA2 functions in the differentiation of respiratory ... Developmental Studies Hybridoma Bank, Department of Biology, Uni- versity of Iowa, Iowa City, IA). Immunohistochemical staining involved six mice per time point and staining for each antibo...

Ngày tải lên: 12/08/2014, 13:22