Báo cáo y học: "HIV-1 protease inhibitor mutations affect the development of HIV-1 resistance to the maturation inhibitor bevirimat" pps
Báo cáo Y học: Conformational analysis by CD and NMR spectroscopy of a peptide encompassing the amphipathic domain of YopD from Yersinia potx
... only transitory, because a portion of YopD is also localized to the host cell cytosol [10]. In addition, we and others observed that a yopD null mutant is constitutively induced for synthesis of ... component of the Yop effector translocon of Yersinia. Mol. Microbiol. 39, 620–632. 10. Francis, M.S. & Wolf-Watz, H. (1998) YopD of Yersinia pseud- otuberculosis is translocated...
Ngày tải lên: 31/03/2014, 21:21
Báo cáo y học: "A 64-week, multicenter, open-label study of aripiprazole effectiveness in the management of patients with schizophrenia or schizoaffective disorder in a general psychiatric outpatient setting" pptx
... subjects; of these, 9 were judged as being unlikely to be related to study drug, 14 as being unrelated to study drug, 11 a s being possibly related to study drug, and 9 as being prob- ably related to ... weeks of long- term treatment. Importantly, improvements in symptoms of schizophrenia were not limited to clinician assessment of symptoms; improvement in quality of lif...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Interactions between IL-32 and tumor necrosis factor alpha contribute to the exacerbation of immune-inflammatory diseases" ppt
... induction of these proinflammatory cytokines may be one of the important mechanisms of IL-32 leading towards inflammation. Although the previous report did not demonstrate the synergizing effect of ... macrophages are known to be important sources of the inflammatory cytokines in the joints of arthritis patients. hIL- Figure 2 IL-32 was abundantly expressed in the sy...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "Does left atrial volume affect exercise capacity of heart transplant recipients" docx
... for attainment of a physiologically valid mea- sure of ventilatory efficiency. The retrospective nature of this study and relatively small sample size are the primary limitations of the pre- sent ... function and therefore, the left atrium may subsequently dilate to increase the reservoir capacity as a compe nsatory mechanism, which in turn theoretically would maintain lef...
Ngày tải lên: 10/08/2014, 09:22
Báo cáo y học: " Psychiatric disorder in early adulthood and risk of premature mortality in the 1946 British Birth Cohort" pdf
... ID of 3 or more (22.0%) who typically have at least 5 psychiatric symptoms and were likely to have a psychiatric disorder; those with an ID of 2 (30.7%), who were mildly symptomatic with 1-4 symptoms; ... mediators only led to a modest reduction in the effect. Sensitivity analyses which excluded the missing category from each of the confounders had little effect either on the...
Ngày tải lên: 11/08/2014, 16:23
Báo cáo y học: "A novel nucleotide insertion in S gene of hepatitis B virus in a chronic carrier" pps
... alter HBsAg antigenicity and affect the binding capacity of anti-HBsAg [25,26]. Due to overlapping of S gene with P gene, variation in S gene may affect catalytic activity of reverse tran- scriptase(rt) ... 3-nt(TCA) deletion from nt491 to nt493(fig- ure 1). Phylogenetic analysis by Mega3.1 software indi- cated they belonged to genotype B. Amino acid sequence analysis of H...
Ngày tải lên: 12/08/2014, 04:20
Báo cáo y học: " Decorin and TGF-β1 polymorphisms and development of COPD in a general population" ppt
... matrix metalloproteases and tis- sue inhibitors of metalloproteases.[27,28] Furthermore, decorin is the natural inhibitor of TGF- β 1 and may there- fore influence the repair process in the lung ... variables. The results of these analyses showed no change in estimates of the variables in the model or a better fit of the model, which indicates that there was no bias...
Ngày tải lên: 12/08/2014, 16:20
Báo cáo khoa học: "Indications and recommended approach for surgical intervention of metastatic disease to the gallbladder" ppt
... lymphadenectomy of the hepatoduodenal ligament [18]. In their review, the authors divided the manage- ment of melanoma of t he gallbladder to pr imary and metastatic lesions. Their review of the ... surgery is an option. Because of the two cases of port-metastases and the small sample size of their study, the authors were unable to advice whether a cholecystect...
Ngày tải lên: 09/08/2014, 03:22
Tài liệu Báo cáo Y học: BIGH3 (TGFBI) Arg124 mutations influence the amyloid conversion of related peptides in vitro Implications in the BIGH3-linked corneal dystrophies pptx
... decades of life and severely impair visual acuity in adulthood. Their therapy is restricted to keratopl- asty and phototherapeutic keratectomy by Excimer laser. Unfortunately, the benefits of these therapies ... peptides to adopt a b-pleated sheet configuration and to form amyloid. The CONH 2 -terminus of the peptides analyzed has an inhibitory Fig. 6. Secondary structure dete...
Ngày tải lên: 21/02/2014, 01:21
Báo cáo Y học: Introducing Wilson disease mutations into the zinc-transporting P-type ATPase ofEscherichia coli The mutation P634L in theÔhingeÕ motif (GDGXNDXP) perturbs the formation of the E2P state pdf
... ATPase activity of the wild-type and mutated enzymes. TheATPaseactivity(percentageoftheactivityofthe wild-type) present in membranes shown. The ATPase activity present in the a bsence of zinc has ... with the recent determination of the crystal structure of the sarco- plasmic Ca-ATPase [4], analysis of these and other WD mutant homologues may help in further d elineating...
Ngày tải lên: 17/03/2014, 17:20