Báo cáo khoa học: Two short protein domains are responsible for the nuclear localization of the mouse spermine oxidase l isoform pdf

... While most of us are familiar with the highly intel- ligible but somewhat robotic sound of synthetic speech, for the approximately 2 million people in the United States with a limited ability ... vocally (Matas et al., 1985), these synthetic voices are inadequate. The restricted number of available voices lack the personalization they de- sire. While intelligibility...

Ngày tải lên: 20/02/2014, 09:20

... k cat values are shown in Table 1. The K m value of wild-type MCAD for octanoyl-CoA, 3.69 lm, compares well with the published value of 3.4 lm [13,14]. Although the K m is increased somewhat for the ... As the reduction in affinity is not as great for R256T, FAD depletion is clearly not responsible for the inactivity of the R256T mutant protein. Thermostabilit...

Ngày tải lên: 20/02/2014, 02:21

... starting points for invasion. The concerted process of opening of the initial double strand and the annealing of the new duplex finally results in either the replacement of the original strand or the expulsion ... the successful achievement of a DG local ⁄ DG global ratio close to unity can be envisioned – either the protein stabilizes structure elements that a...

Ngày tải lên: 14/02/2014, 19:20

... the effect of AG1478 on the viabil- ity of human NSCLC cell line PC-9. Treatment of the cells with AG1478 markedly suppressed the cell viabil- ity, as determined by the results of a colorimetric ... instructions. The Cell Counting Kit-8 is a colorimetric method in which the intensity of the dye is proportional to the number of the viable cells. Briefly, 200 lL...

Ngày tải lên: 18/02/2014, 13:20

... ignore, practically all extracellular cues used for building and patterning the embryo. Generally, with the appearance of primordial germ cells (PGCs), the germ line is usually the earliest cell-lineage ... strongly suggest that stem cell niches, areas with a certain sig- nal–molecule cocktail, are responsible for the final out- come of BMP signaling, be it by modulating...

Ngày tải lên: 19/02/2014, 00:20

... LG domains with the Ig domains of Axl. Gas6 LG domains are in cyan (N-terminal segment and LG1) and green (LG2), and Axl Ig domains are in yellow (IG1) and brown (IG2); a calcium ion in the LG1–LG2 ... epithelial cells [45]. A similar apop- totic cell clearance function for protein S may indeed also occur in the testis, as Leydig cells express protein S [46] and they...

Ngày tải lên: 19/02/2014, 05:20

... and 0.5 mL fractions collected. The molecular mass of the complex was estimated from the column by comparison with the elution volumes of c-globulin, bovine serum albumin, ovalbumin, myoglobin and ... the fibroblast and T-cell complexes were identical (Fig. 4E). The CCV1 complex therefore forms on a functional element in the IL-2 5¢-UTR in T cells. The VEGF 5¢-UTR CCV1 comp...

Ngày tải lên: 19/02/2014, 12:20

... poor recovery of activity during purification. The thermal lability of the larger AFP contrasts with the ‘elasticity’ of the smaller AFP. Although these short, monomeric helical AFP are 50% denatured ... point of seawater calls into question the functional significance of the small type I AFP in these species. Considering the levels of these AFPs in the plasma it...

Ngày tải lên: 20/02/2014, 01:20

... couM be dealt with separately. Yet the following reading for 10a, which would result from the application of the lambda-abstraction scheme to the two predicates, is emphatically not the correct ... 2. the modifier semantic relation 3. the filler of this semantic relation 4. a binary coercion relation The following is the top-level phrasal representation for...

Ngày tải lên: 20/02/2014, 21:20

... in a small exception table, the problem of "multiple regular" patterns usually increases the size of this table dra- matically. For example, there are two ways to plu- ralize a noun ... will automatically create a strong bias for the selection of the other member of the pair, if the latter is compatible with the semantic concept being lexicalized....

Ngày tải lên: 20/02/2014, 22:20